*part 1a. involves absolutely no cylons
since diagnostic testing (as i mentioned in my last blog) is soooooooo cheap here. i’m about to have a boat-load of it! for all you lab geeks out there, this may be interesting. for everyone else, pardon this boring list! here’s what all i’m checking out in round one of testing:
the first big question: am i ovulating??
1. lh–luteinizing hormone is produced in women’s anterior (front) pituitary. but let’s back up… at the beginning of a woman’s cycle, another hormone (fsh, “follicle stimulating hormone”) prompts an egg follicle to form on the surface of the ovary. when this follicle is ready to pop out its little egg, it secretes progesterone, which blocks estrogen, and when a woman’s estrogen therefore drops mid-cycle, a big burst of luteinizing hormone is released, causing the woman to ovulate (release her egg). so really, women are just giant hormonal rube goldberg machines–and you WONDER why we’re sometimes nuts!
if there is no lh surge, then there is no ovulation, so you can gather a lot of information by testing for lh. if you’ve ever taken at home ovulation tests, this was what those little strips were looking for. a blue line means lh surge is on and ovulation will occur in the next 12 hours.
i’m finding out how to get the strips here in india. wish me luck!
2. serum progesterone–this one is a blood test, not a pee stick, but we have a nurse on staff here, so hopefully my hopeless veins will be found. so when you ovulate, the little follicle that used to house the egg turns into what’s known as the “corpus luteum” (yellow body) which acts as a temporary endocrine organ and secretes progesterone (pro-“gest”, pregnancy-supporting) until (hopefully) the placenta can take over the job when you become pregnant.
if for whatever reason you have low progesterone, your body may not be able to support a pregnancy (until the issue is corrected). estrogen and progesterone are like opposite ends of a magnet. when one is high, the other is generally low. each inhibits the other, and both cycle through once-monthly highs and lows. if one is too high (dominance) the other can be too low (deficiency), and vice versa. if one step of the rube goldberg machine is out of place, every step that comes after it will be affected.
to test progesterone, you can either take blood once on day 21 of a 28 day cycle (value should be 20-25), or you can take it 5, 7, and 9 days post ovulation and add the values (should add to 30). i think i’ll go for the three-day test, just to get the most coverage.
if my progesterone is low, it’s probably because my estrogen is high. fat cells produce estrogen, and if there’s one thing i’ve got, it’s fat cells. luckily this means that treatment involves weight loss and not horrid hormonal therapy or anything.
3. pelvic ultrasound–who knows what all they can and can’t see with this one, but it’s only $20 US, so what’s the harm in trying? ultrasound should help me rule out things like polycystic ovarian syndrome, endometriosis, or the presence of wacky masses. some sources say ultrasound can help identify any scarring on the fallopian tubes as well, which will let me know if anything is impeding egg travel.
4. charting–the thing that i like the most about charting is that it’s like opening a little window into your hormonal world. charting involves waking up each morning and taking your basal body temperature and checking cervical fluid. you then chart this information onto a graph and use the plotted graph to predict ovulation (look up fertility awareness method if you’re interested in knowing more). a friend is making me some snazzy charts, so i’m excited to start this.
if these tests don’t give me clarity, we’ll move on to round 1.b which involves more blood tests and imaging. when working on a differential diagnosis, it’s best to start with the most likely and move on to the least likely. we call this horses and zebras. if you hear hoof-beats in the hallway, your mind should go to horses first and THEN zebras 🙂 testing for zebras can come later, but hopefully it doesn’t come at all.
many thanks to steven snyder for pow-wowing with me about my plan 🙂 i’ll let y’all know results in a month or two.
to be continued…